Table 3 |
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|
Putative and known antimicrobial drug and heavy metal resistance genes in the S. maltophilia K279a genome sequence |
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Substrate |
Gene |
Putative gene product |
|
|
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|
Aminoglycoside |
Smlt0191 |
Putative aminoglycoside phosphotransferase |
|
Aminoglycoside |
Smlt1669 |
Putative aminoglycoside 2' N-acetyltransferase |
|
Aminoglycoside |
Smlt2120 |
Known aminoglycoside 3' phosphotransferase |
|
Streptomycin |
Smlt2336 |
Putative streptomycin 3" phosphotransferase/kinase |
|
Aminoglycoside |
Smlt3615 |
Known aminoglycoside 6'N acetyltransferase |
|
Spectinomycin |
Smlt2125/spcN |
Putative spectinomycin phosphotransferase |
|
Chloramphenicol |
Smlt0620/cat |
Putative chloramphenicol acetyltransferase |
|
Fluoroquinolone |
Smlt1071/qnrB |
Putative quinolone resistance protein |
|
Macrolides |
Smlt0032 |
Putative MFS-type tripartite efflux transporter |
|
Macrolides |
Smlt1537-9 |
Putative ABC-type tripartite efflux transporter |
|
Macrolides |
Smlt2642-3 |
Putative ABC efflux transporter and MFP |
|
Multidrug |
Smlt1528-30/emrA,emrB |
Putative MFS-type tripartite efflux transporter |
|
Multidrug |
Smlt1830-31;33/smeVWX |
Putative RND-type tripartite efflux transporter |
|
Multidrug |
Smlt2201-2/smeYZ |
Putative RND-type efflux protein and MFP |
|
Multidrug |
Smlt2796-8 |
Multidrug/fusaric acid resistance protein |
|
Multidrug |
Smlt3170-1/smeGH |
Putative RND-type efflux protein and MFP |
|
Multidrug |
Smlt3787-78/smeMN |
Putative RND-type efflux protein and MFP |
|
Multidrug |
Smlt3924-25/smeOP |
Putative RND-type efflux protein and MFP |
|
Multidrug |
Smlt4072-74/smeDEF |
Known RND-type tripartite efflux protein |
|
Multidrug |
Smlt4279-81/smeJKL |
Putative RND-type tripartite efflux proteins and MFP |
|
Multidrug |
Smlt4474-76/smeABC |
Known RND-type tripartite efflux protein |
|
Beta-lactams |
blaL1 |
Known Beta-lactamase - L1 |
|
Beta-lactams |
blaL2 |
Known Beta-lactamase - L2 |
|
Kasuagamycin |
ksgA |
Putative kasuagamycin resistance protein |
|
Organic solvents |
ostA |
Organic solvent tolerance protein |
|
Peroxide |
ohrA |
Organic hydroperoxide |
|
Mercury |
merRTPA |
Mercury resistance |
|
Copper |
copLABMGCDF Smlt2445/Smlt2443 copL2A2B2 copCD |
Copper resistance |
|
Arsenic |
arsRCHR2C2B Smlt2420 |
Arsenic resistance |
|
|
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Crossman et al. Genome Biology 2008 9:R74 doi:10.1186/gb-2008-9-4-r74 |
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