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Porin new light onto chromatin and nuclear organization

Lee E Finlan and Wendy A Bickmore

Author Affiliations

MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh, EH4 2XU, UK

Genome Biology 2008, 9:222  doi:10.1186/gb-2008-9-5-222

Published: 16 May 2008

Abstract

A recent report identifies sites in the human genome that can associate with nucleoporin 93, a subunit of the nuclear pore complex. These associations are modulated by levels of global histone acetylation and highlight the dynamic nature of chromatin organization in the nucleus.