Genome Biology

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Estrogen, not intrinsic aging, is the major regulator of delayed human wound healing in the elderly

Matthew J Hardman and Gillian S Ashcroft

Author Affiliations

Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK

Genome Biology 2008, 9:R80 doi:10.1186/gb-2008-9-5-r80

Published: 13 May 2008

Additional files

Additional data file 1:

All probe sets identified as differentially expressed using the filtering criteria fold change (±7-fold), q-value (<0.1) and expression level (>15).

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Additional data file 2:

Subset S1: Dragon database-derived estrogen-regulated probe sets.

Format: DOC Size: 71KB Download file

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Additional data file 3:

Subset S2: mouse dataset-derived estrogen-regulated probe sets.

Format: DOC Size: 68KB Download file

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Additional data file 4:

Subset S3: hand-annotated estrogen-regulated probe sets.

Format: DOC Size: 115KB Download file

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Additional data file 5:

EASE experimental readout.

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Additional data file 6:

Subset S4: GenAge-derived aging-associated probe sets.

Format: DOC Size: 33KB Download file

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Additional data file 7:

Subset S5: hand-curated and aging-associated GO probe sets.

Format: DOC Size: 59KB Download file

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Additional data file 8:

Differentially expressed genes identified in this study, using a relaxed array filtering criteria, that have also been demonstrated to alter life-span in animal models.

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Additional data file 9:

Primers used for qPCR.

Format: DOC Size: 80KB Download file

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