Table 1

Summary of genes implicated in gastric function in platypus

Protein

Gene

Status in platypus genome

Confirmatory evidence


ATPase, H+/K+ exchanging, α polypeptide

ATP4A

Absent

Southern blot

ATPase, H+/K+ exchanging, β polypeptide

ATP4B

Pseudogene

PCR/direct sequencing

Cathepsin E

CTSE

Pseudogene

PCR/direct sequencing

Gastrin

GAST

Absent

Southern blot

Neurogenin 3

NGN3

Absent

Southern blot

Pepsin A

PGA

Absent

Southern blot/sequencing

Pepsin C

PGC

Absent

Southern blot/sequencing

Gastric intrinsic factor

GIF

Present (expression pancreatic)

RT-PCR

Chymosin

CYMP

Present (expression not detected)

Sequencing/RT-PCR


RT,-PCR, reverse transcription polymerase chain reaction.

Ordoñez et al. Genome Biology 2008 9:R81   doi:10.1186/gb-2008-9-5-r81

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