Table 1

Summary of genes implicated in gastric function in platypus

Protein
Gene
Status in platypus genome
Confirmatory evidence

ATPase, H+/K+ exchanging, α polypeptide
ATP4A
Absent
Southern blot
ATPase, H+/K+ exchanging, β polypeptide
ATP4B
Pseudogene
PCR/direct sequencing
Cathepsin E
CTSE
Pseudogene
PCR/direct sequencing
Gastrin
GAST
Absent
Southern blot
Neurogenin 3
NGN3
Absent
Southern blot
Pepsin A
PGA
Absent
Southern blot/sequencing
Pepsin C
PGC
Absent
Southern blot/sequencing
Gastric intrinsic factor
GIF
Present (expression pancreatic)
RT-PCR
Chymosin
CYMP
Present (expression not detected)
Sequencing/RT-PCR

RT,-PCR, reverse transcription polymerase chain reaction.

Ordoñez et al. Genome Biology 2008 9:R81   doi:10.1186/gb-2008-9-5-r81