Table 2 |
||||
|
Summary of patient population and invasive characteristics of corresponding stem cell cultures in vitro |
||||
|
Patient number |
Age (years) |
Origin |
Gleason score |
% Invasion in vitro* |
|
|
||||
|
228 |
- |
LN metastasis |
7 |
101 ± 21 |
|
434 |
59 |
Prostate |
8/9 |
99 ± 56 |
|
484 |
69 |
Prostate |
7 |
105 ± 29 |
|
512 |
74 |
Prostate |
BPH |
- |
|
561 |
72 |
Prostate |
BPH |
- |
|
563 |
64 |
Prostate |
7 |
35 ± 9.5 |
|
569 |
64 |
Prostate |
8 |
75 ± 9 |
|
574 |
74 |
Prostate |
BPH/G6 (5%) |
- |
|
605 |
56 |
LN metastasis |
7 |
119 ± 21 |
|
661 |
78 |
Prostate |
6 |
- |
|
627 |
79 |
Prostate |
BPH |
- |
|
662 |
66 |
Prostate |
BPH |
- |
|
665 |
53 |
Prostate |
7 |
63 ± 18.4 |
|
667 |
47 |
Prostate |
6 |
61 ± 4.2 |
|
687 |
63 |
Prostate |
7 |
74 |
|
690 |
79 |
Prostate |
BPH |
- |
|
693 |
75 |
Prostate |
BPH |
- |
|
704 |
64 |
Prostate |
7 (HR) |
- |
|
003/06 |
52 |
Prostate |
6 |
- |
|
|
||||
|
*Invasion assays were carried out on total epithelial cell populations before fractionation according to [4]. Positive controls for invasive capacity were cell lines MCF7 and PC3M whose invasion score was 18-36%, whereas normal cell lines PNT2 and PNT1a and BPH/primary normal prostate invasion scores ranged from 3-6%. Patient 704 was being treated (hormone refractory (HR)) by androgen blockade therapy. |
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|
Birnie et al. Genome Biology 2008 9:R83 doi:10.1186/gb-2008-9-5-r83 |
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