Genome Biology

official impact factor 6.89

Open Access Research

A computational model of gene expression reveals early transcriptional events at the subtelomeric regions of the malaria parasite, Plasmodium falciparum

Matthias Scholz* and Martin J Fraunholz

Author Affiliations

Competence Center for Functional Genomics, Ernst-Moritz-Arndt University, Friedrich-Ludwig-Jahn Strasse, D-17487 Greifswald, Germany

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Genome Biology 2008, 9:R88 doi:10.1186/gb-2008-9-5-r88

Published: 27 May 2008

Additional files

Additional data file 1:

P. falciparum genes included in the circular PCA analysis.

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Additional data file 2:

Subtelomeric genes among the 100 top-regulated genes of P. falciparum HB3.

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Additional data file 3:

Internal genes among the 100 top-regulated genes of P. falciparum HB3.

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Additional data file 4:

Forty down-regulated genes with the steepest expression slopes resulting from a comparative analysis of P. falciparum strains HB3, 3D7, and Dd2 at approximately 22 h.

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Additional data file 5:

Animation of the IDC based on gene activities of strain P. falciparum HB3.

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Additional data file 6:

Animation of the IDC based on change of expression rates of strain P. falciparum HB3.

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Additional data file 7:

Distances of members of Plasmodium multigene families from the telomeres.

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Additional data file 8:

Additional methods and detailed information on the data pre-filtering process.

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