Figure 9.

Snapshot of a comparison of the expression slopes of genes of P. falciparum strains HB3 (3,639 genes), 3D7 (2,419), and Dd2 (2,718) at approximately 22 h of the IDC. Genes were pre-filtered by quality criteria described in Material and methods. Note the similar characteristics of subtelomeric down-regulation and a burst of transcriptional activation throughout large parts of internal chromosome regions. Additional data file 4 lists the top 40 down-regulated genes of this comparative analysis for each of the analyzed strains.