Table 2

Summary of histopathological diagnoses and severities

Severity


Histopathological diagnosis

None

Minimal

Mild

Moderate

Marked


Centrilobular hepatocyte necrosis

304

65

15

8

26

Centrilobular, mid-zonal hepatocyte necrosis

399

8

5

4

2

Mid-zonal hepatocyte necrosis

417

1

0

0

0

Focal hepatocyte necrosis

392

11

12

2

1

Centrilobular cellular infiltrates

333

50

17

13

5

Centrilobular, mid-zonal cellular infiltrates

400

5

8

5

0

Portal cellular infiltrates

394

16

5

3

0

Focal cellular infiltrates

370

34

10

4

0

Depletion glycogen

324

19

33

16

26

Centrilobular hepatocyte degeneration

403

9

3

3

0

Centrilobular, mid-zonal hepatocyte degeneration

402

4

7

5

0

Hepatocyte apoptosis

410

7

1

0

0

Hepatocyte hypertrophy

382

10

16

0

10

Hepatocyte fatty change

416

2

0

0

0

Bile duct hyperplasia

405

11

2

0

0

Congestion

397

10

5

6

0

Hemorrhage

384

34

0

0

0

Hepatocyte regeneration

412

3

0

2

1

Mitosis

393

12

5

4

4


Lobenhofer et al. Genome Biology 2008 9:R100   doi:10.1186/gb-2008-9-6-r100

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