Table 2 |
|||||
|
Summary of histopathological diagnoses and severities |
|||||
|
Severity |
|||||
|
|
|||||
|
Histopathological diagnosis |
None |
Minimal |
Mild |
Moderate |
Marked |
|
|
|||||
|
Centrilobular hepatocyte necrosis |
304 |
65 |
15 |
8 |
26 |
|
Centrilobular, mid-zonal hepatocyte necrosis |
399 |
8 |
5 |
4 |
2 |
|
Mid-zonal hepatocyte necrosis |
417 |
1 |
0 |
0 |
0 |
|
Focal hepatocyte necrosis |
392 |
11 |
12 |
2 |
1 |
|
Centrilobular cellular infiltrates |
333 |
50 |
17 |
13 |
5 |
|
Centrilobular, mid-zonal cellular infiltrates |
400 |
5 |
8 |
5 |
0 |
|
Portal cellular infiltrates |
394 |
16 |
5 |
3 |
0 |
|
Focal cellular infiltrates |
370 |
34 |
10 |
4 |
0 |
|
Depletion glycogen |
324 |
19 |
33 |
16 |
26 |
|
Centrilobular hepatocyte degeneration |
403 |
9 |
3 |
3 |
0 |
|
Centrilobular, mid-zonal hepatocyte degeneration |
402 |
4 |
7 |
5 |
0 |
|
Hepatocyte apoptosis |
410 |
7 |
1 |
0 |
0 |
|
Hepatocyte hypertrophy |
382 |
10 |
16 |
0 |
10 |
|
Hepatocyte fatty change |
416 |
2 |
0 |
0 |
0 |
|
Bile duct hyperplasia |
405 |
11 |
2 |
0 |
0 |
|
Congestion |
397 |
10 |
5 |
6 |
0 |
|
Hemorrhage |
384 |
34 |
0 |
0 |
0 |
|
Hepatocyte regeneration |
412 |
3 |
0 |
2 |
1 |
|
Mitosis |
393 |
12 |
5 |
4 |
4 |
|
|
|||||
|
Lobenhofer et al. Genome Biology 2008 9:R100 doi:10.1186/gb-2008-9-6-r100 |
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