Table 1

Mouse SuperArray data showing greater than twofold cell cycle RNA expression changes in the cerebellum of Wlds mice compared with wild-type controls
Gene name
 Symbol
 Acc. Number
 Array cell
 Fold change
 SD
 Cell cycle function
V-abl Abelson murine leukemia oncogene 1
 Abl1
 NM_009594
 A01
 21.91
 1.74
 Regulation
Cyclin B1
 Ccnb1
 NM_172301
 A12
 5.50
 0.65
 M phase and regulation
Antigen identified by monoclonal antibody Ki 67
 Mki67
 XM_133912
 D09
 4.23
 0.41
 S phase and DNA replication
Cyclin A2
 Ccna2
 NM_009828
 A11
 3.85
 0.65
 Regulation
G protein-coupled receptor 132
 Gpr132
 NM_019925
 C11
 3.73
 0.82
 G1 phase and G1/S transition
Checkpoint kinase 1 homolog
 Chek1
 NM_007691
 C01
 2.74
 0.81
 G2 phase and G2/M transition
Transformation related protein 63
 Trp63
 NM_011641
 G10
 2.53
 0.06
 Negative regulator
Cyclin-dependent kinase 2
 Cdk2
 NM_016756
 B07
 2.43
 0.52
 M phase
Calcium/calmodulin-dependent protein kinase II, beta
 Camk2b
 NM_007595
 A08
 2.41
 0.10
 G1 phase and G1/S transition
S-phase kinase-associated protein 2 (p45)
 Skp2
 NM_013787
 F12
 2.40
 0.26
 G1 phase and G1/S transition and regulation
Wee 1 homolog
 Wee1
 NM_009516
 G12
 2.33
 0.02
 M phase
Meiotic recombination 11 homolog A
 Mre11a
 NM_018736
 D10
 2.28
 0.57
 S phase and DNA replication
CDC28 protein kinase 1b
 Cks1b
 NM_016904
 C02
 2.23
 0.49
 Checkpoint and arrest and regulation
Breast cancer 2
 Brca2
 NM_009765
 A06
 2.23
 0.63
 M phase and regulation and checkpoint and arrest
Cyclin C
 Ccnc
 NM_016746
 B02
 2.07
 0.12
 regulation
Transcription factor Dp 1
 Tfdp1
 NM_009361
 G07
 2.07
 0.06
 Regulation
SMT3 suppressor of mif two 3 homolog 1
 Sumo1
 NM_009460
 G04
 2.04
 0.13
 S phase and DNA replication
Retinoblastoma-like 2
 Rbl2
 NM_011250
 F08
 2.01
 0.25
 Negative regulator

SD, standard deviation.

Wishart et al. Genome Biology 2008 9:R101   doi:10.1186/gb-2008-9-6-r101

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