Table 2

The amount of genomic DNA in which methods agree (%)

IsoFinder

GC-Profile

BASIO

Least-squares

Consensus

Average*


IsoFinder

100.0

62.2

74.8

58.8

82.3

65.3

GC-Profile

62.2

100.0

59.9

83.1

72.8

68.4

BASIO

74.8

59.9

100.0

60.9

85.5

65.2

Least-squares

58.8

83.1

60.9

100.0

73.7

67.6

Consensus

82.3

72.8

85.5

73.7

100.0

78.6


Percentage of the human genome classified into the same isochore families by each pair of methods. The amount of equally classified human DNA ranges from 59-86% in an all-against-all pairwise comparison. On average, all methods agree in about 66% of the genome. The consensus isochore map has the best agreement of 79%, on average, with all other methods. *The average agreement of the method in the respective row with all other methods except itself and the consensus isochore map.

Schmidt and Frishman Genome Biology 2008 9:R104   doi:10.1186/gb-2008-9-6-r104

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