Genome Biology

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The hidden universal distribution of amino acid biosynthetic networks: a genomic perspective on their origins and evolution

Georgina Hernández-Montes, J Javier Díaz-Mejía, Ernesto Pérez-Rueda and Lorenzo Segovia*

Genome Biology 2008, 9:R95 doi:10.1186/gb-2008-9-6-r95

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Amino acids biosynthesis and nitrogen assimilation pathways: a great genomic deletion during eukaryotes evolution

RLM Guedes, F Prosdocimi, GR Fernandes, LK Moura, HAL Ribeiro, JM Ortega BMC Genomics 2011, 12(Suppl 4):S2 (22 December 2011)

Research article   Open Access Highly Accessed

Identification of network topological units coordinating the global expression response to glucose in Bacillus subtilis and its comparison to Escherichia coli

Carlos Vázquez, Julio A Freyre-González, Guillermo Gosset, José Loza, Rosa Gutiérrez-Ríos BMC Microbiology 2009, 9:176 (24 August 2009)

Research   Open Access Highly Accessed

The conservation and evolutionary modularity of metabolism

José M Peregrín-Alvarez, Chris Sanford, John Parkinson Genome Biology 2009, 10:R63 (12 June 2009)

A novel evolutionary analysis of metabolic networks across 26 taxa reveals a highly-conserved but flexible core of metabolic enzymes.

Hypothesis   Open Access Highly Accessed

An extension of the coevolution theory of the origin of the genetic code

Massimo Di Giulio Biology Direct 2008, 3:37 (5 September 2008)

This article is part of a collection on Origin and early evolution...

A modification of the coevolution theory of the origin of the genetic code suggesting that the biosynthetic pathways of amino acids imprinted the genetic code organization early on.