Table 2

MSigDB C2 gene sets most significantly enriched in groups 1-3

Upregulated genes

Downregulated genes


Group 1

eDEV500

lDEV500

STEMCELL_NEURAL_UP

SANSOM_APC_5_DN

eDEV200

NAKAJIMA_MCS_UP

TARTE_PLASMA_BLASTIC

TARTE_MATURE_PC

STEMCELL_EMBRYONIC_UP

CALCIUM_REGULATION_IN_CARDIAC_CELLS

PRMT5_KD_UP

LEE_DENA_DN

CANCER_NEOPLASTIC_META_UP

SMOOTH_MUSCLE_CONTRACTION

LI_FETAL_VS_WT_KIDNEY_DN

YAO_P4_KO_VS_WT_UP

eDEV100

lDEV200

MOREAUX_TACI_HI_IN_PPC_UP

LEE_ACOX1_DN

Group 2

HOFFMANN_BIVSBII_BI_TABLE2

FLECHNER_KIDNEY_TRANSPL_REJ_DN

YU_CMYC_UP

AGEING_KIDNEY_SPECIFIC_DN

DNA_REPLICATION_REACTOME

CHANG_SERUM_RESPONSE_DN

eDEV500

LE_MYELIN_DN

SERUM_FIBROBLAST_CORE_UP

AGEING_KIDNEY_DN

CMV_IE86_UP

VENTRICLES_UP

CHANG_SERUM_RESPONSE_UP

CARIES_PULP_DN

G1_TO_S_CELL_CYCLE_REACTOME

UVB_NHEK1_UP

PEART_HISTONE_DN

SMOOTH_MUSCLE_CONTRACTION

GENOTOXINS_ALL_4HRS_REG

BRCA_ER_POS

Group 3

SERUM_FIBROBLAST_CELLCYCLE

FLECHNER_KIDNEY_TRANSPL_REJ_DN

BRCA_ER_NEG

AGEING_KIDNEY_DN

TARTE_MATURE_PC

IDX_TSA_UP_CLUSTER6

DAC_PANC_UP

AGEING_KIDNEY_SPECIFIC_DN

SANSOM_APC_5_DN

DIAB_NEPH_DN

NAKAJIMA_MCS_UP

CARIES_PULP_DN

CANCER_UNDIFFERENTIATED_META_UP

MITOCHONDRIA

HIF1_TARGETS

BRCA_ER_POS

LEE_TCELLS3_UP

VENTRICLES_UP

GENOTOXINS_ALL_4HRS_REG

HEARTFAILURE_ATRIA_DN


Naxerova et al. Genome Biology 2008 9:R108   doi:10.1186/gb-2008-9-7-r108

Open Data