Table 3 |
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|
Example genes from the consensus sets of groups 1-3 ordered by their average rank across all DTs |
||||
|
ProbeID |
Average rank |
Gene symbol |
Description |
|
|
|
||||
|
Consensus group 1 |
||||
|
Early |
201577_at |
627.1 |
NME1* |
Non-metastatic cells 1, protein (NM23A) |
|
200812_at |
633.8 |
CCT7 |
Chaperonin containing TCP1, subunit 7 (eta) |
|
|
201202_at |
875.7 |
PCNA |
Proliferating cell nuclear antigen |
|
|
205436_s_at |
890.0 |
H2AFX |
H2A histone family, member X |
|
|
201476_s_at |
904.6 |
RRM1 |
Ribonucleotide reductase M1 polypeptide |
|
|
200910_at |
922.9 |
CCT3 |
Chaperonin containing TCP1, subunit 3 (gamma) |
|
|
202330_s_at |
924.1 |
UNG |
Uracil-DNA glycosylase |
|
|
202503_s_at |
1060.0 |
KIAA0101* |
KIAA0101 |
|
|
222077_s_at |
1146.2 |
RACGAP1 |
Rac GTPase activating protein 1 |
|
|
204170_s_at |
1188.5 |
CKS2 |
CDC28 protein kinase regulatory subunit 2 |
|
|
Consensus group 2 |
||||
|
Early |
204766_s_at |
530.6 |
NUDT1 |
Nudix (nucleoside diphosphate linked moiety X)-type motif 1 |
|
204825_at |
629.0 |
MELK |
Maternal embryonic leucine zipper kinase |
|
|
203270_at |
636.6 |
DTYMK |
Deoxythymidylate kinase (thymidylate kinase) |
|
|
218585_s_at |
768.5 |
DTL |
Denticleless homolog (Drosophila) |
|
|
220085_at |
772.6 |
HELLS |
Helicase, lymphoid-specific |
|
|
Late |
205741_s_at |
3587.9 |
DTNA |
Dystrobrevin, alpha |
|
204279_at |
3816.5 |
PSMB9 |
Proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) |
|
|
204416_x_at |
3944.6 |
APOC1 |
Apolipoprotein C-I |
|
|
202307_s_at |
3987.2 |
TAP1 |
Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
|
|
209040_s_at |
4243.6 |
PSMB8 |
Proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) |
|
|
Consensus group 3 |
||||
|
Early |
204825_at |
629.0 |
MELK |
Maternal embryonic leucine zipper kinase |
|
202503_s_at |
1060.0 |
KIAA0101* |
KIAA0101 |
|
|
202705_at |
1095.9 |
CCNB2 |
Cyclin B2 |
|
|
222077_s_at |
1146.2 |
RACGAP1 |
Rac GTPase activating protein 1 |
|
|
204170_s_at |
1188.5 |
CKS2 |
CDC28 protein kinase regulatory subunit 2 |
|
|
Late |
208997_s_at |
3296.1 |
UCP2 |
Uncoupling protein 2 (mitochondrial, proton carrier) |
|
205798_at |
3499.9 |
MMP7 |
Matrix metallopeptidase 7 (matrilysin, uterine) |
|
|
202307_s_at |
3724.7 |
PPGB |
Protective protein for beta-galactosidase (galactosialidosis) |
|
|
209166_s_at |
3946.3 |
IL7R |
Interleukin 7 receptor |
|
|
206707_x_at |
3987.2 |
TAP1 |
Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
|
|
208812_x_at |
4485.7 |
HLA-C |
Major histocompatibility complex, class I, C |
|
|
|
||||
|
To identify only the most relevant genes, the definition of 'consensus gene set' was tightened from the definition employed in Figure 7. Consensus group 1 = 20 genes overexpressed in at least 15/16 data sets belonging to group 1; consensus group 2 = 58 genes overexpressed in all data sets (6/6) belonging to group 2; consensus group 3 = 29 genes overexpressed in 9/13 data sets belonging to group 3. Bold entries are those expressed more than three times above median in at least one of murine E6, E7, E8, E9, E10 (Symatlas). Italicized entries are those expressed more than three times above median in at least one of the following human cell types: CD4+ T cells, CD8+ T cells, CD19+ B cells (peripheral blood), BDCA4+ dendritic cells, B lymphoblasts (peripheral blood). *Expression data not available in Symatlas. |
||||
|
Naxerova et al. Genome Biology 2008 9:R108 doi:10.1186/gb-2008-9-7-r108 |
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