Glaucoma disease-associated genes differentially regulated in glaucomatous OHN astrocytes. Differential expression of six glaucoma disease associated genes (BMP1, AMIGO2, DMPK, SLIT2, RBP-1 and CASK) was validated by qRT-PCR in human ONH astrocytes. Genes were normalized to 18S. Graphical representation of the relative mRNA levels in normal and glaucomatous AA and normal and glaucomatous CA astrocytes (n = 6, two-tailed t-test). Asterisk indicates p < 0.05).
Lukas et al. Genome Biology 2008 9:R111 doi:10.1186/gb-2008-9-7-r111