TEM images of the novel cell forms. (a-b) TEM images of the plasmid control strain pSOS95del: typical elongated clostridial form with electron translucent granulose (a); typical endospore form with a developing endospore at one end of the cell and electron translucent granulose still visible at the other end of the cell (b). (c-d) TEM images of the antisense strain asCAP0167. (e-f) TEM images of the antisense strain asCAC1766. Red arrows in (c-f) indicate pinched portions of the cell membrane not seen in the control strain and are characteristic of this novel cell type. Also noticeable is the electron dense granulose in the antisense strains, in contrast to the electron translucent granulose in the control samples.
Jones et al. Genome Biology 2008 9:R114 doi:10.1186/gb-2008-9-7-r114