The tachyzoite expressed proteome: comparison with EST and microarray expression data. A comparison of the expressed proteome of tachyzoites with EST and microarray data reveals discrepancies between protein and transcriptional data. (a) Venn diagram comparing the correlation between the number of non-redundant release4 genes detected by EST expression from T. gondii tachyzoite and bradyzoites (available from ToxoDB) and those detected by this proteome study. The number of genes unique to each intersection is indicated. (b) Venn diagrams comparing the correlation between release4 genes obtained by this proteome study and those detected by microarray analysis of RH strain tachyzoites, including those genes with expression of ≥ 25 and ≥ 50 percentiles. (c) Bar chart showing the number of release4 genes also detected by proteomics for each of the four percentile ranges, 0-24%, 25-49%, 50-74%, 75-100%, determined by microarray analysis.
Xia et al. Genome Biology 2008 9:R116 doi:10.1186/gb-2008-9-7-r116