|
Comparing the results of RAMA to the averaged log ratios on the HIV data and the like and like data |
|||
| Data |
Benchmark |
RAMA |
Averaged log ratio |
|
|
|||
| HIV data |
13 positive controls |
All 13 positive controls have log ratios >1 |
All 13 positive controls have log ratios >1 |
| 24 negative controls |
All 24 negative controls have log ratios <1 |
3 negative controls have log ratios >1 |
|
| Like and like data |
No genes expected to be differentially expressed |
All log ratios <1 |
6 genes with log ratios >1 |
|
RAMA produced the desired results on both datasets while the averaged log ratio produced three and six false positives, respectively, on these two datasets. | |||
Chu et al. Genome Biology 2008 9:R118 doi:10.1186/gb-2008-9-7-r118 |
|||