Table 2 |
||||||||
|
Major biological processes modified in the cultured CD8+ NKT-like cells |
||||||||
|
≥5 fold (314) |
≥10 fold (113) |
|||||||
|
|
|
|||||||
|
Biological process |
Number of genes |
% genes |
p-value |
OR |
Number of genes |
% genes |
p-value |
OR |
|
|
||||||||
|
Immunity and defense |
56 |
17.80% |
2.0E-11 |
3.1 |
35 |
31.00% |
7.7E-15 |
6.3 |
|
Apoptosis |
25 |
8.00% |
8.8E-10 |
4.8 |
19 |
16.80% |
2.2E-13 |
11.3 |
|
Lipid, fatty acid metabolism |
25 |
8.00% |
7.5E-06 |
2.9 |
6 |
5.30% |
0.1161 |
1.9 |
|
Signal transduction |
74 |
23.60% |
3.4E-05 |
1.8 |
28 |
24.80% |
0.0041 |
1.9 |
|
Cell structure and motility |
25 |
8.00% |
0.0004 |
2.2 |
11 |
9.70% |
0.0036 |
2.8 |
|
Cell cycle |
23 |
7.30% |
0.0004 |
2.3 |
11 |
9.70% |
0.0015 |
3.1 |
|
Oncogenesis |
14 |
4.50% |
0.0005 |
3.0 |
8 |
7.10% |
0.0004 |
4.9 |
|
Protein metabolism and modification |
60 |
19.10% |
0.0009 |
1.6 |
23 |
20.40% |
0.0152 |
1.8 |
|
Cell proliferation and differentiation |
21 |
6.70% |
0.0023 |
2.1 |
13 |
11.50% |
0.0001 |
3.8 |
|
Carbohydrate metabolism |
14 |
4.50% |
0.0053 |
2.3 |
2 |
1.80% |
0.6720 |
0.9 |
|
Sulfur metabolism |
5 |
1.60% |
0.0059 |
4.6 |
0 |
|||
|
Other metabolism |
13 |
4.10% |
0.0159 |
2.0 |
6 |
5.30% |
0.0319 |
2.6 |
|
Cell adhesion |
12 |
3.80% |
0.0528 |
1.7 |
6 |
5.30% |
0.0424 |
2.5 |
|
Others |
176 |
56.10% |
53 |
24.80% |
||||
|
|
||||||||
|
OR, odds ratio. |
||||||||
|
Zhou et al. Genome Biology 2008 9:R119 doi:10.1186/gb-2008-9-7-r119 |
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