Table 3

Transcription factors differentially expressed in CD8+ NKT-like cells

Symbol

Function

NKT/nCD8

CD4/nCD8

aCD8/nCD8

NKT/nCD8 (q)

CD4/nCD8 (q)

aCD8/nCD8 (q)


Nfil3

NF

19.7

22.3

4.3

4.0E-04

3.6E-04

3.4E-02

Mycn (Nmyc1)

TF

20.8

2.2

1.1

8.0E-05

2.7E-02

6.8E-01

Irf8 (Icsbp1)

TF

14.4

1.9

19.2

1.7E-04

3.2E-02

3.7E-03

Irf4

TF

4.7

24.7

18.2

1.6E-03

4.7E-05

6.2E-03

Litaf

TF

10.3

5.0

4.8

4.5E-05

1.4E-04

1.6E-02

Runx2

TF

8.6

3.5

1.8

2.2E-04

5.2E-02

3.4E-01

Pbx3

TF

5.8

6.2

1.6

4.1E-04

4.8E-04

3.6E-01

Jun (AP1)

TF

5.8

2.9

2.6

8.9E-04

8.8E-02

1.2E-01

Cgrrf1

TF

4.9

4.9

2.8

2.2E-04

2.7E-03

7.7E-02

Eomes

TF

4.0

0.2

0.6

9.7E-04

3.8E-04

4.5E-01

Atf4

TF

3.8

2.0

3.1

6.4E-03

3.1E-03

2.0E-02

Zbtb32 (Rog)

TF (ZF)

9.3

1.8

3.9

1.2E-03

3.9E-02

1.6E-02

Zdhhc2

TF (ZF)

4.9

2.6

1.5

9.3E-04

1.5E-03

4.6E-01

Zfp313

TF (ZF)

4.3

2.2

1.2

1.9E-02

6.6E-03

6.8E-01

Zfp608

TF (ZF)

3.9

1.2

1.7

4.2E-04

1.1E-01

1.3E-01

Rnf128

TF (RF)

6.2

10.4

1.0

5.8E-04

7.8E-04

8.0E-01

Rnf13

TF (RF)

4.0

1.7

1.2

8.5E-04

7.3E-02

7.0E-01

Socs2

Suppressor

48.6

104.0

27.8

3.5E-05

3.3E-05

3.9E-03

Cish (Socs)

Suppressor

8.8

9.5

4.9

1.2E-04

5.2E-05

1.3E-02

Tcf7

TF

0.012

0.061

0.274

5.7E-07

1.4E-03

7.7E-02

Klf3

TF (KR)

0.012

0.014

0.034

9.4E-08

5.9E-06

8.1E-03

Klf2

TF (KR)

0.04

0.03

0.01

4.3E-04

5.5E-04

2.7E-03

Klf1

TF (KR)

0.05

0.05

0.06

3.5E-05

1.7E-04

1.0E-02

Rkhd3

TF (RF)

0.15

0.17

0.16

1.1E-04

1.7E-04

9.1E-03

Bcl11a

TF (ZF)

0.15

0.16

0.15

2.4E-04

1.1E-03

2.3E-02

Zbtb20

TF (ZF)

0.20

0.15

0.16

1.2E-04

3.2E-04

6.3E-03


NKT, CD8+ NKT-like cells; nCD8, naïve CD8+ T cells; cCD4, cultured CD4+ T cells; aCD8, activated CD8+ T cells. KR, Kruppel-like factor; NF, nuclear factor; RF, ring finger; TF, transcription factor; ZF, zinc finger. The table is split into two parts based on the expression ratio of NKT/nCD8.

Zhou et al. Genome Biology 2008 9:R119   doi:10.1186/gb-2008-9-7-r119

Open Data