Table 5

Gene expression levels for genes encoding critical surface markers

Symbol

Function

NKT/nCD8

CD4/nCD8

aCD8/nCD8

NKT/nCD8 (q)

CD4/nCD8 (q)

aCD8/nCD8 (q)


Ifitm1

Suppression

89.9

7.1

1.5

2.8E-07

2.2E-03

2.4E-01

Lilrb4 (ILT3)

Suppression

50.3

43.8

7.6

3.6E-04

4.0E-05

5.6E-03

Ifitm2

Suppression

45.6

11.4

1.6

6.0E-07

2.1E-03

2.8E-01

Havcr2 (Tim3)

Suppression

36.5

10.4

0.7

1.6E-04

2.0E-03

2.4E-01

Tnfrsf9 (4-1BB)

Suppression

28.2

12.5

12.8

2.4E-04

3.2E-03

1.1E-02

Tnfsf6 (FASL)

Suppression

24.4

4.3

3.2

1.2E-05

6.1E-02

4.5E-02

Ifitm3

Suppression

24.3

15.6

0.8

2.5E-05

1.4E-03

6.6E-01

Ctla4

Suppression

5.3

18.7

21.5

2.8E-03

4.8E-03

2.7E-03

Tnfrsf18 (GITR)

Suppression

4.8

11.1

4.4

2.7E-03

4.3E-05

1.7E-02

Pdcd1lg2

Suppression

4.6

7.3

3.3

5.4E-04

2.5E-04

3.0E-02

Icos

Suppression

4.6

4.0

3.6

2.8E-03

3.5E-03

3.2E-02

Tnfsf11 (RANKL)

Suppression

3.9

8.1

27.0

7.6E-03

2.4E-03

3.4E-03

Tnfsf10 (TRAIL)

Suppression

3.1

3.2

1.8

2.7E-03

9.5E-03

6.6E-02

Tnfrsf4 (OX40)

Suppression

3.0

23.8

11.3

1.6E-02

7.6E-06

5.7E-03

P2ry14 (Gpr105)

Receptor

65.4

6.9

1.1

2.1E-05

2.3E-03

6.8E-01

Fcer1g

Receptor

12.7

0.7

0.7

7.4E-04

1.4E-02

2.2E-01

Ptger3

Receptor

12.0

1.2

1.1

3.5E-04

2.3E-01

6.9E-01

Il12rb1

Receptor

10.6

11.3

4.0

8.9E-04

2.7E-05

1.8E-02

Ltb4r1

Receptor

8.8

1.2

0.9

2.9E-03

1.8E-01

7.0E-01

Gabarapl1

Receptor

8.7

5.3

3.4

2.4E-04

1.8E-03

1.4E-01

Ly6a

Receptor

7.3

11.3

3.0

3.5E-04

1.7E-04

5.3E-02

Tcrg

Receptor

6.3

0.2

0.3

1.9E-03

1.4E-03

6.9E-02

Il12rb2

Receptor

5.8

18.2

6.2

1.1E-04

1.6E-04

1.0E-02

Pilrb

Receptor

5.8

0.9

0.8

1.1E-03

1.5E-01

5.2E-01

Tmem2

Receptor

5.8

4.6

2.0

5.4E-03

8.5E-04

1.1E-01

Gpr171

Receptor

4.6

7.4

2.9

8.8E-03

1.3E-03

1.2E-01

Gpr34

Receptor

4.5

0.6

0.7

2.7E-02

1.1E-02

3.6E-01

Gpr160

Receptor

3.7

1.1

1.4

4.8E-03

3.0E-01

3.5E-01

Oprm1

Receptor

0.20

0.08

0.49

1.6E-03

3.6E-04

1.1E-01

Tlr1

Receptor

0.12

0.11

0.19

1.3E-04

3.5E-04

2.2E-02

Trat1

Receptor

0.12

0.15

0.25

1.3E-04

2.2E-03

4.3E-02

Edg1

Receptor

0.10

0.17

0.13

2.9E-04

1.0E-02

3.0E-02

Il2ra (CD25)

CR

48.4

66.9

28.1

1.7E-05

1.2E-05

2.7E-03

Il2rb (CD122)

CR

7.1

4.3

1.9

1.4E-03

1.4E-03

2.7E-01

Il7r

CR

0.12

0.17

0.05

3.4E-04

1.0E-04

4.9E-03

Il6ra

CR

0.11

0.26

0.16

6.3E-06

1.0E-02

9.2E-03

Il6st

CR

0.08

0.11

0.16

2.7E-07

3.7E-05

5.3E-03

Sema6d

Costimulation

6.1

0.9

1.4

2.1E-02

3.2E-01

2.5E-01

Pdcd1

Costimulation

4.5

4.0

4.6

8.3E-03

5.2E-03

1.7E-02

Ptger2

Costimulation

4.5

18.3

5.3

1.1E-04

6.8E-05

1.5E-02

Cd28

Costimulation

4.0

6.3

2.2

2.0E-03

2.6E-04

1.1E-01

Cd80

Costimulation

3.6

2.1

1.3

7.8E-03

5.3E-03

4.7E-01

Cd24a

Costimulation

0.03

0.82

0.78

4.2E-04

2.8E-01

6.4E-01

Ccr5

CCR

18.3

3.9

1.6

1.1E-05

4.3E-04

1.4E-01

Ccr2

CCR

15.7

0.7

0.5

2.4E-04

6.1E-02

4.0E-02

Cxcr6

CCR

5.0

1.9

0.1

5.5E-03

1.9E-01

3.6E-02

Ccr7

CCR

0.10

0.39

1.43

1.1E-03

6.2E-02

7.0E-01

Cxcr4

CCR

0.06

0.46

0.10

6.3E-06

2.1E-02

9.2E-03

Ccr9

CCR

0.03

0.03

0.04

3.1E-07

7.6E-06

2.7E-03

Adam8

Adhesion

16.9

6.1

0.8

3.9E-04

4.4E-03

4.5E-01

Tjp1

Adhesion

14.6

0.4

0.4

2.9E-05

6.7E-03

5.0E-02

Emp1

Adhesion

14.4

13.7

1.3

1.2E-03

2.2E-03

6.3E-01

Emilin2

Adhesion

13.6

0.8

1.1

2.4E-04

2.0E-01

7.6E-01

Itgav

Adhesion

10.6

3.6

2.3

3.6E-05

1.0E-03

8.1E-02

Nov

Adhesion

10.6

1.0

1.1

1.4E-02

4.3E-01

7.5E-01

Alcam

Adhesion

8.2

18.3

8.5

3.0E-04

2.9E-04

1.9E-02

Cdh1

Adhesion

6.9

0.8

0.9

3.3E-03

8.6E-02

6.2E-01

Adam9

Adhesion

6.9

7.1

2.3

4.0E-04

1.2E-03

2.6E-01

Tjp2

Adhesion

5.7

4.7

2.0

1.8E-04

9.1E-05

1.0E-01

Dsc2

Adhesion

5.0

0.9

0.9

5.8E-02

2.0E-01

7.1E-01

Itga6

Adhesion

0.14

0.12

0.48

4.2E-04

1.6E-04

1.5E-01

Itgae

Adhesion

0.08

0.10

0.09

3.8E-06

7.1E-05

4.2E-03

Sell (CD62L)

Adhesion

0.04

0.23

0.19

2.4E-04

3.6E-04

1.4E-02


NKT, CD8+ NKT-like cells; nCD8, naïve CD8+ T cells; cCD4, cultured CD4+ T cells; aCD8, activated CD8+ T cells. CCR, chemokine receptor; CR, cytokine receptor.

Zhou et al. Genome Biology 2008 9:R119   doi:10.1186/gb-2008-9-7-r119

Open Data