Different domain combinations in innate immunity receptor families. Numbers of different domains that combine with an individual TIR or NACHT domain in each designated genome are displayed. 'Average of all domains' (purple bars) means the average of domain combinations over all domains found in a genome. A detailed list of partner domains that combine with TIR or NACHT in each genome is given in Additional data file 4. The absolute numbers differ slightly when different Ensembl protein datasets or thresholds are used, but the relative fluctuations between different genomes are the same.
Zhang et al. Genome Biology 2008 9:R123 doi:10.1186/gb-2008-9-8-r123