Genome Biology

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The miR-17-5p microRNA is a key regulator of the G1/S phase cell cycle transition

Nicole Cloonan1, Mellissa K Brown1, Anita L Steptoe1, Shivangi Wani1, Wei L Chan1, Alistair RR Forrest3,1, Gabriel Kolle1, Brian Gabrielli2 and Sean M Grimmond1*

Author Affiliations

1 Institute for Molecular Bioscience, The University of Queensland, Carmody Road, St Lucia, 4072, Australia

2 Diamantina Institute for Cancer, Immunology and Metabolic Medicine, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, 4102, Australia

3 Genomic Sciences Center, RIKEN Yokohama Institute, Yokohama, 230-0045 Japan

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Genome Biology 2008, 9:R127 doi:10.1186/gb-2008-9-8-r127

Published: 14 August 2008

Additional files

Additional data file 1:

G1/S associated mRNAs predicted to be targets of miR-17-5p.

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Additional data file 2:

Validation of miR-17-5p activity in stable HEK293T cell lines over-expressing miR-17-5p.

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Additional data file 3:

An interactive version of this figure where literature support and gene/protein information can be viewed through IPA is available [24].

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Additional data file 4:

Primers used in this study.

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