Table 1

Dysregulated genes (compared to B6 expression levels) in M. spretus and the IRCSs

All genes considered




     Pan genomic (37,432)
SEG
44H
137F
97C
     Under-expressed
3,290
57
15
26
     Over-expressed
3,560
19
45
2
     ∑
6,850
76
60
28
     Percentage of modified genes
20.90
0.23
0.18
0.09
     Proportion of under-expressed (%)
48.0
75.0
25.0
92.9





Only genes inside B6 segments considered




     Genetic background (variable number according to the strain)

44H
137F
97C
     Under-expressed

21
2
11
     Over-expressed

3
30
0
     ∑

24
32
11
     Percentage of modified genes

0.06
0.09
0.03
     Proportion of under-expressed (%)

87.5
6.3
100.0

A statistical overview of genes with modified expression in the various genomic contexts examined in this study, compared to the B6 strain taken as a reference.

L'Hôte et al. Genome Biology 2008 9:R133   doi:10.1186/gb-2008-9-8-r133

Open Data