Table 2 |
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|
Total correlations in expression levels for the different mice of this study |
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| Correlation coefficients between expression levels |
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|
|
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| All transcripts (37,432) |
All transcripts in the 11 segments (2,320) |
Modifed transcripts in the M. spretus segments (144) |
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|
|
|
|
||||
| Correlation coefficient |
p-value |
Correlation coefficient |
p-value |
Correlation coefficient |
p-value |
|
|
|
||||||
| B6 versus IRCSs |
0.9905 |
<0.0001 |
0.9646 |
<0.0001 |
0.6899 |
<0.0001 |
| SEG versus IRCSs |
0.8846 |
<0.0001 |
0.9038 |
<0.0001 |
0.5963 |
<0.0001 |
| B6 versus SEG |
0.8921 |
<0.0001 |
0.8919 |
<0.0001 |
0.3243 |
0.002 |
|
|
||||||
|
Total correlations for the fluorescence levels of the various transcripts between the two parent species and the IRCSs taken as a whole. Three classes are considered, either with all the genes detectable on the array, or only the genes present inside the M. spretus segments, or only genes modified at the 4X threshold inside these segments. While even inside the M. spretus segments most genes are not dysregulated, a class of genes that are strictly driven by the M. spretus context appears, since the correlation between the IRCSs and SEG does not significantly decrease when the B6 parental effect is removed (from 0.5963 to 0.5441; see Table 3). |
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|
L'Hôte et al. Genome Biology 2008 9:R133 doi:10.1186/gb-2008-9-8-r133 |
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