Table 1

Evolution of telomere-end-binding proteins containing the OB fold

Species

OB-fold proteins

Structure

Budding yeast

CDC13-Stn1-Ten1, Est3

RPA-like

Fission yeast

POT1-TPP1

TEBPα/β-like

Ciliate

TEBPα-TEBPβ

TEBPα/β heterodimer

Vertebrates (frogs to humans)

POT1-TPP1

TEBPα/β-like

Xin et al. Genome Biology 2008 9:232   doi:10.1186/gb-2008-9-9-232