Table 5

Clusters of genes deregulated in trx mutants conserved in other phylogenetically related species

Genes (orthologs)

Species

Genome

↑

↓

Clusters ↑

Clusters ↓

Clusters

Deregulated genes in clusters

D. melanogaster

19,670

260

275

10

15

25

97

D. simulans

17,927

235

262

7

13

20

75

D. yakuba

19,929

259

275

11

14

25

96

D. pseudoobscura

15,096

170

230

1

13

14

60

A. gambiae

7,283

97

151

2

5

7

34

For each species, we show: number of genes for which an ortholog in D. melanogaster was found, number of orthologs for up-regulated genes, number of orthologs for down-regulated genes, number of up-regulated clusters, number of down-regulated clusters, total number of clusters, number of deregulated genes from D. melanogaster that constitute the clusters.

Blanco et al. Genome Biology 2008 9:R134   doi:10.1186/gb-2008-9-9-r134