Genome Biology

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Segmentation-based detection of allelic imbalance and loss-of-heterozygosity in cancer cells using whole genome SNP arrays

Johan Staaf, David Lindgren, Johan Vallon-Christersson, Anders Isaksson, Hanna Göransson, Gunnar Juliusson, Richard Rosenquist, Mattias Höglund, Åke Borg and Markus Ringnér*

Genome Biology 2008, 9:R136 doi:10.1186/gb-2008-9-9-r136

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BioMed Central: 5 citations

Method   Open Access Highly Accessed

A statistical approach for detecting genomic aberrations in heterogeneous tumor samples from single nucleotide polymorphism genotyping data

Christopher Yau, Dmitri Mouradov, Robert N Jorissen, Stefano Colella, Ghazala Mirza, Graham Steers, Adrian Harris, Jiannis Ragoussis, Oliver Sieber, Christopher C Holmes Genome Biology 2010, 11:R92 (21 September 2010)

OncoSNP is a method for detecting CNVs in tumors from SNP array data that can account for contaminating healthy tissue.

Method   Open Access Highly Accessed

Analysis of the copy number profiles of several tumor samples from the same patient reveals the successive steps in tumorigenesis

Eric Letouzé, Yves Allory, Marc A Bollet, François Radvanyi, Frédéric Guyon Genome Biology 2010, 11:R76 (22 July 2010)

TuMult is a method for reconstructing the history of cancer progression from copy number variations in several samples from a patient

Research article   Open Access

A new analysis tool for individual-level allele frequency for genomic studies

Hsin-Chou Yang, Hsin-Chi Lin, Mei-Chu Huang, Ling-Hui Li, Wen-Harn Pan, Jer-Yuarn Wu, Yuan-Tsong Chen BMC Genomics 2010, 11:415 (5 July 2010)

Research article   Open Access

An integrated Bayesian analysis of LOH and copy number data

Paola MV Rancoita, Marcus Hutter, Francesco Bertoni, Ivo Kwee BMC Bioinformatics 2010, 11:321 (15 June 2010)

Methodology article   Open Access Highly Accessed

Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios

Johan Staaf, Johan Vallon-Christersson, David Lindgren, Gunnar Juliusson, Richard Rosenquist, Mattias Höglund, Åke Borg, Markus Ringnér BMC Bioinformatics 2008, 9:409 (2 October 2008)