Table 2 |
||||||
|
Estimation of tumor cell content from simulated data using segmentation |
||||||
|
Tumor |
Tumor cells using hemizygous loss (%)* |
Tumor cells using single copy gain (%)† |
Tumor cells using copy neutral LOH (%)‡ |
|||
|
|
|
|
||||
|
cells (%) |
Paired |
Unpaired |
Paired |
Unpaired |
Paired |
Unpaired |
|
|
||||||
|
0 |
- |
- |
- |
- |
- |
- |
|
5 |
- |
- |
- |
- |
- |
- |
|
10 |
- |
- |
- |
- |
- |
- |
|
15 |
- |
- |
- |
- |
15 |
15 |
|
20 |
- |
- |
- |
- |
21 |
21 |
|
25 |
26 |
26 |
- |
- |
25 |
25 |
|
30 |
30 |
30 |
31 |
31 |
30 |
30 |
|
35 |
35 |
35 |
36 |
36 |
35 |
35 |
|
40 |
40 |
40 |
41 |
41 |
40 |
40 |
|
45 |
45 |
45 |
45 |
45 |
45 |
45 |
|
50 |
50 |
50 |
50 |
50 |
49 |
49 |
|
55 |
55 |
55 |
55 |
55 |
55 |
55 |
|
60 |
59 |
59 |
60 |
60 |
60 |
61 |
|
65 |
65 |
65 |
65 |
65 |
64 |
65 |
|
70 |
70 |
70 |
70 |
70 |
69 |
70 |
|
75 |
75 |
75 |
75 |
75 |
75 |
75 |
|
80 |
80 |
80 |
80 |
80 |
80 |
80 |
|
85 |
85 |
85 |
85 |
85 |
85 |
84 |
|
90 |
90 |
90 |
90 |
90 |
89 |
86 |
|
95 |
95 |
93 |
96 |
96 |
94 |
88 |
|
100 |
99 |
95 |
101 |
101 |
97 |
89 |
|
|
||||||
|
*Hemizygous loss on chromosome 10q23.1-q23.33. †Mono allelic gain on chromosome 8p. ‡Copy neutral LOH on 17p13.1-p12. Dashes indicate 'not detected'. |
||||||
|
Staaf et al. Genome Biology 2008 9:R136 doi:10.1186/gb-2008-9-9-r136 |
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