Table 2

Estimation of tumor cell content from simulated data using segmentation

Tumor

Tumor cells using hemizygous loss (%)*

Tumor cells using single copy gain (%)

Tumor cells using copy neutral LOH (%)




cells (%)

Paired

Unpaired

Paired

Unpaired

Paired

Unpaired


0

-

-

-

-

-

-

5

-

-

-

-

-

-

10

-

-

-

-

-

-

15

-

-

-

-

15

15

20

-

-

-

-

21

21

25

26

26

-

-

25

25

30

30

30

31

31

30

30

35

35

35

36

36

35

35

40

40

40

41

41

40

40

45

45

45

45

45

45

45

50

50

50

50

50

49

49

55

55

55

55

55

55

55

60

59

59

60

60

60

61

65

65

65

65

65

64

65

70

70

70

70

70

69

70

75

75

75

75

75

75

75

80

80

80

80

80

80

80

85

85

85

85

85

85

84

90

90

90

90

90

89

86

95

95

93

96

96

94

88

100

99

95

101

101

97

89


*Hemizygous loss on chromosome 10q23.1-q23.33. Mono allelic gain on chromosome 8p. Copy neutral LOH on 17p13.1-p12. Dashes indicate 'not detected'.

Staaf et al. Genome Biology 2008 9:R136   doi:10.1186/gb-2008-9-9-r136

Open Data