Yong Zhang1*
, Tao Liu1*
, Clifford A Meyer1
, Jérôme Eeckhoute2
, David S Johnson3
, Bradley E Bernstein4,5
, Chad Nussbaum5
, Richard M Myers6
, Myles Brown2
, Wei Li7
and X Shirley Liu1 
1
Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute and Harvard School of Public Health, 44 Binney Street, Boston, MA 02115, USA
2
Division of Molecular and Cellular Oncology, Department of Medical Oncology, Dana-Farber Cancer Institute and Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA
3
Gene Security Network, Inc., 2686 Middlefield Road, Redwood City, CA 94063, USA
4
Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital and Department of Pathology, Harvard Medical School, 13th Street, Charlestown, MA 02129, USA
5
Broad Institute of Harvard and MIT, 7 Cambridge Center, Cambridge, MA, 02142, USA
6
Department of Genetics, Stanford University Medical Center, Stanford, CA 94305, USA
7
Division of Biostatistics, Dan L Duncan Cancer Center, Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA