Research
Evolutionary rate and gene expression across different brain regions
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* Corresponding authors: Tamir Tuller tamirtul@post.tau.ac.il - Eytan Ruppin ruppin@post.tau.ac.il
1 School of Computer Sciences, Tel Aviv University, Ramat Aviv 69978, Israel
2 Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Ramat Aviv 69978, Israel
3 School of Medicine, Tel Aviv University, Ramat Aviv 69978, Israel
Genome Biology 2008, 9:R142 doi:10.1186/gb-2008-9-9-r142
Published: 23 September 2008Additional files
Additional data file 1:
Presented is a table listing various parameters of the analyzed genes.
Format: XLS Size: 16.7MB Download file
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Additional data file 2:
Presented is a table listing the GO enrichments for the genes that are over-expressed in the cortical regions.
Format: XLS Size: 372KB Download file
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Additional data file 3:
Presented is a table listing the GO enrichments for the genes that are over-expressed in the subcortical regions.
Format: XLS Size: 1MB Download file
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Additional data file 4:
Presented is a table listing the GO enrichment categories for the genes that are under expressed in the cortical and in the subcortical brain regions.
Format: XLS Size: 33KB Download file
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Additional data file 5:
Presented are the Supplementary notes (Supplementary notes 1 to 6).
Format: DOC Size: 37KB Download file
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Additional data file 6:
Presented is a table that includes the ER/expression correlation and ER in each mouse tissue.
Format: XLS Size: 20KB Download file
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Additional data file 7:
Presented is a table that includes the ER/expression correlation in the chimp brain tissues.
Format: XLS Size: 14KB Download file
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Additional data file 8:
Presented is a figure that depicts the following: (A) median ER (human lineage) in brain tissues and other tissues; (B) median ER in each brain region; (C) the correlation between ER (human lineage) and expression level in each tissue; and (D) the correlation between ER and the expression levels in each brain region.
Format: DOC Size: 8.2MB Download file
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Additional data file 9:
Presented is a figure that depicts the following: (A) median ER (human-mouse dN/dS) in brain tissues and other tissues; and (B) the correlation between ER (human-mouse dN/dS) and expression level in each tissue.
Format: DOC Size: 10.2MB Download file
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Additional data file 10:
Presented is a figure that depicts the mean correlation of expression levels with ER (human lineage), for regions belonging to five different embryonic developmental origins.
Format: DOC Size: 1.3MB Download file
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Additional data file 11:
Presented is a figure that depicts the mean ER (mouse-human) for regions belonging to five different embryonic developmental origins.
Format: DOC Size: 1.3MB Download file
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Additional data file 12:
Presented is a table listing various properties of the analyzed tissues.
Format: XLS Size: 30KB Download file
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Additional data file 13:
Presented is a table that includes the mouse gene expression and ER.
Format: XLS Size: 4.1MB Download file
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Additional data file 14:
Presented is a table with the set of organisms that was used for estimating gene ages.
Format: DOC Size: 86KB Download file
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Additional data file 15:
Presented is a table that includes the phyletic patterns of all the human genes.
Format: XLS Size: 8.5MB Download file
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