Genome Biology

official impact factor 6.89

This article is part of the supplement: Quantitative inference of gene function from diverse large-scale datasets

Open Access Method

Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function

Weidong Tian1, Lan V Zhang1,4, Murat Taşan1, Francis D Gibbons1,5, Oliver D King1,6, Julie Park2, Zeba Wunderlich1,7, J Michael Cherry2 and Frederick P Roth1,3*

Author Affiliations

1 Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Longwood Avenue, Boston, Massachusetts 02115, USA

2 Department of Genetics, School of Medicine, Stanford University, Stanford, California 94305-5120, USA

3 Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Jimmy Fund Way, Boston, Massachusetts 02115, USA

4 McKinsey and Company, Hansen Way, Palo Alto, California 94304, USA

5 Merrimack Pharmaceuticals, Kendall Square, Cambridge, Massachusetts 02139, USA

6 Boston Biomedical Research Institute (BBRI), Grove St., Watertown, Massachusetts 02472, USA

7 Massachusetts Institute of Technology, Massachusetts Ave, Cambridge, Massachusetts 02139, USA

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Genome Biology 2008, 9(Suppl 1):S7 doi:10.1186/gb-2008-9-s1-s7

Published: 27 June 2008

Additional files

Additional data file 1:

Expert evaluation of GO predictions by Funckenstein.

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Open Data