Genome Biology

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Open Access Research

Coding region structural heterogeneity and turnover of transcription start sites contribute to divergence in expression between duplicate genes

Chungoo Park and Kateryna D Makova*

Author Affiliations

Center for Comparative Genomics and Bioinformatics, Department of Biology, The Pennsylvania State University, University Park, PA 16802, USA

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Genome Biology 2009, 10:R10 doi:10.1186/gb-2009-10-1-r10

Published: 28 January 2009

Additional files

Additional data file 1:

Classification of duplicate gene pairs based on the absence or presence of shared TSSs and different duplication mechanisms.

Format: EPS Size: 422KB Download file

Open Data

Additional data file 2:

Number of duplicate gene pairs that were identified by the FASTA and TRIBE-MCL methods.

Format: EPS Size: 389KB Download file

Open Data

Additional data file 3:

The identities were obtained by BL2SEQ [70] with default parameters. Black bars represent 110 bp (-20 bp to +90 bp) surrounding each TSS.

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Additional data file 4:

Number of duplicate gene pairs (A) with shared TSSs and (B) without shared TSSs plotted against the instantaneous rate of KS.

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Open Data

Additional data file 5:

Proportions of group A duplicate gene pairs with shared TSSs depending on different identity thresholds.

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Additional data file 6:

Number of duplicate gene pairs in different structure categories plotted against the instantaneous rate of KS.

Format: EPS Size: 444KB Download file

Open Data