Table 2

Multiple regression models for expression divergence in duplicate genes

Predictors

P-value

RCVE*


Cis

4.2 × 10-2 (NS)

0.075

TSS§

9.9 × 10-5

0.277

Tandem

2.7 × 10-6

0.405

KA × Cis

1.1 × 10-2 (NS)

0.118

KS × Cis

2.7 × 10-2 (NS)

0.088

Structure¥ × Tandem

1.7 × 10-3

0.180

TSS × Tandem

1.1 × 10-5

0.354

ω# × Cis

3.1 × 10-3

0.159

R2

0.093


*RCVE: relative contribution to the variability explained (see Materials and methods for more details). Cis: divergence of cis-regulatory sequences in 2 kb surrounding TSS (see Materials and methods for more details). NS: not significant after Bonferroni correction for multiple tests. §TSS: shared versus not shared TSSs. Tandem: tandem versus nontandem organization of duplicate genes. ¥Structure: structural heterogeneity in coding sequences. #ω:KA/KS ratio.

Park and Makova Genome Biology 2009 10:R10   doi:10.1186/gb-2009-10-1-r10

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