Table 4

Motif enrichment for genes with EG links to FOX-1 and FOX-2

Human

Mouse

FOX-1(A2BP1)

FOX-2(RBM9)

Fox-1(A2bp1)

Fox-2(Rbm9)

Number of exons with EG links to FOX-1 or FOX-2

64

21

19

5

Number of GCAUG occurrences among exons with EG links to FOX- 1 or FOX-2

96

28

21

9

Average number of GCAUG occurrences among 1,000 simulated exon groups

49.4

16.6

15.8

4.2

P-value of the motif enrichment

0.000

0.031

0.172

0.060

Exons with EG links to FOX-1 or FOX-2 were assembled. The occurrences of GCAUG were calculated for those exon groups. To test the significance of the motif enrichment, we simulated exon groups by randomly selecting exons. The p-value of the motif enrichment was calculated as Pr (the motif frequency in the simulated exon group ≥ the observed motif frequency) from 1,000 simulations.

Chen and Zheng Genome Biology 2009 10:R3   doi:10.1186/gb-2009-10-1-r3