Genome Biology

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Comparing cellular proteomes by mass spectrometry

Florian Fröhlich and Tobias C Walther*

Author Affiliations

Organelle Architecture and Dynamics, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried/Munich, Germany

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Genome Biology 2009, 10:240 doi:10.1186/gb-2009-10-10-240

Published: 28 October 2009

Abstract

Mass spectrometry and cryo-electron tomography together enable the determination of the absolute and relative abundances of proteins and their localization, laying the groundwork for comprehensive systems analyses of cells.