Software
A compiled and systematic reference map of nucleosome positions across the Saccharomyces cerevisiae genome
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* Corresponding author: B Franklin Pugh bfp2@psu.edu
1 Center for Eukaryotic Gene Regulation, 456 North Frear Laboratory, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA
2 Current address: The School of Life Sciences and Technology, Tongji University, Shanghai, 200065, PR China
Genome Biology 2009, 10:R109 doi:10.1186/gb-2009-10-10-r109
Published: 8 October 2009Abstract
Nucleosomes have position-specific functions in controlling gene expression. A complete systematic genome-wide reference map of absolute and relative nucleosome positions is needed to minimize potential confusion when referring to the function of individual nucleosomes (or nucleosome-free regions) across datasets. We compiled six high-resolution genome-wide maps of Saccharomyces cerevisiae nucleosome positions from multiple labs and detection platforms, and report new insights. Data downloads, reference position assignment software, queries, and a visualization browser are available online http://atlas.bx.psu.edu/ webcite.