Genome Biology

official impact factor 6.89

Open Access Research

Preferential binding of HIF-1 to transcriptionally active loci determines cell-type specific response to hypoxia

Xiaobo Xia and Andrew L Kung*

Author Affiliations

Department of Pediatric Oncology, Dana-Farber Cancer Institute, Children's Hospital Boston, and Harvard Medical School, Binney Street, Boston, MA 02115, USA

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Genome Biology 2009, 10:R113 doi:10.1186/gb-2009-10-10-r113

Published: 14 October 2009

Additional files

Additional data file 1:

All HIF-1 bound regions identified by ChIP-chip in U87 cells.

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Open Data

Additional data file 2:

GSEA analysis of HIF-1 binding and hypoxia-induced gene expression.

Format: PDF Size: 1.8MB Download file

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Open Data

Additional data file 3:

HIF-1 binding associations with RNA Pol II and H3K4 me3.

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Open Data

Additional data file 4:

All common HIF-1-bound loci identified by ChIP-chip in U87 cells and HepG2 cells.

Format: PDF Size: 71KB Download file

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Open Data