Genome Biology

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Enrichment of sequencing targets from the human genome by solution hybridization

Ryan Tewhey1,2, Masakazu Nakano1,4, Xiaoyun Wang1,4, Carlos Pabón-Peña3, Barbara Novak3, Angelica Giuffre3, Eric Lin3, Scott Happe3, Doug N Roberts3, Emily M LeProust3, Eric J Topol1, Olivier Harismendy1,4* and Kelly A Frazer1,4*

Author Affiliations

1 Scripps Genomic Medicine, Scripps Translational Science Institute, The Scripps Research Institute, 3344 N. Torrey Pines Court, La Jolla, CA 92037, USA

2 Division of Biological Sciences, University of California San Diego, 9500 Gilman Dr., La Jolla, CA 92093, USA

3 Agilent Technologies, Inc., 5301 Stevens Creek Blvd., Santa Clara, CA 95051, USA

4 Current address: Moores UCSD Cancer Center, 3855 Health Sciences Drive 0901, La Jolla, CA 92093-0901, USA

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Genome Biology 2009, 10:R116 doi:10.1186/gb-2009-10-10-r116

Published: 16 October 2009

Additional files

Additional data file 1:

Contiguous genomic intervals targeted in the present study

Format: XLS Size: 31KB Download file

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Additional data file 2:

Genes and ECS targeted in the present study

Format: XLS Size: 106KB Download file

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Additional data file 3:

Discordant positions and the variant characteristics in each targeting sequencing experiment

Format: XLSX Size: 61KB Download file

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Additional data file 3:

Probes designed using eArray

Format: XLS Size: 4MB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data