Open Access Research

Serum-dependent transcriptional networks identify distinct functional roles for H-Ras and N-Ras during initial stages of the cell cycle

Esther Castellano12, Carmen Guerrero1, Alejandro Núñez1, Javier De Las Rivas1 and Eugenio Santos1*

Author Affiliations

1 Centro de Investigación del Cáncer, IBMCC (CSIC-USAL), University of Salamanca, Campus Unamuno, 37007 Salamanca, Spain

2 Current address: Signal Transduction Laboratory, Cancer Research UK London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3PX, UK

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Genome Biology 2009, 10:R123  doi:10.1186/gb-2009-10-11-r123

Published: 6 November 2009

Additional files

Additional data file 1:

Table S1: differential gene expression in ras knockout fibroblasts after serum starvation. Table S2: differential gene expression in serum starved, G0-arrested WT fibroblasts after incubation of cell cultures in the presence of serum for 1 hour. Table S3: differential gene expression in serum-starved, G0-arrested WT fibroblasts after stimulation with serum for 8 hours. Table S4: differential gene expression in serum-starved, G0-arrested H-ras-/- fibroblast cultures after stimulation with serum for 1 hour. Table S5: differential gene expression in serum-starved, G0-arrested N-ras-/- fibroblasts after incubation of cell cultures in the presence of serum for 1 hour. Table S6: differential gene expression in serum-starved, G0-arrested H-ras-/-/N-ras-/- fibroblasts after incubation of cell cultures in the presence of serum for 1 hour. Table S7: differential gene expression in serum-starved, G0-arrested H-ras-/- fibroblasts after incubation of cell cultures in the presence of serum for 8 hours. Table S8: differential gene expression in serum-starved, G0-arrested N-ras-/- fibroblasts after incubation of cell cultures in the presence of serum for 8 hours. Table S9: differential gene expression in serum-starved, G0-arrested H-ras-/-/N-ras-/- fibroblasts after incubation of cell cultures in the presence of serum for 8 hours. Table S10: antibodies used in reverse phase protein microarrays.

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