Table 1

Evolutionary signatures and other properties of ncRNAs

macroRNA

lincRNA


Transcripts or intervals

3,051

1,675

Exons

5,893

2,126

Mouse-human exonic alignments ≥100 bp

3,537

1,784

Median dexon (mouse-human)

0.418

0.426

Median G+C fraction

0.418

0.430

Median dexon/dAR (mouse-human)

0.887

0.904

Fold enrichment of IPSs

1.73

1.77

Fold enrichment of PhastCons 17-way

2.2

2.6

Fold enrichment of Evofold predictions

1.4

0.8

Fold enrichment with transcription factor genes*

1.7

2.4

Rare alleles/intermediate alleles

978/2,675

369/1,110

Constrained exons

1393

595

Promoters

1802

504

Mouse-human promoter alignments ≥100 bp

1477

460

Median dpro (mouse-human)

0.366

0.402

Median dpro/dAR (mouse-human)

0.787

0.857


*Measured as the fold-enrichment within protein coding gene territories (see Materials and methods) associated with the Gene Ontology term 'regulation of transcription'.

Marques and Ponting Genome Biology 2009 10:R124   doi:10.1186/gb-2009-10-11-r124

Open Data