Table 5 |
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The 37 classifiers discriminated sepsis caused by B. pseudomallei from those by other organisms |
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|
Rank |
Abbreviation |
Gene name |
Gene accession |
|
|
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|
1 |
FAM26F |
Homo sapiens family with sequence similarity 26, member F |
[GenBank:NM_001010919.1] |
|
2 |
MYOF |
Myoferlin, transcript variant 2 |
[GenBank:NM_133337.2] |
|
3 |
LAP3 |
Leucine aminopeptidase 3 |
[GenBank:NM_015907.2] |
|
4 |
HLA-DMA |
Major histocompatibility complex, class II, DM alpha |
[GenBank:NM_006120.3] |
|
5 |
WARS |
Tryptophanyl-tRNAsynthetase (WRS) |
[GenBank:M61715.1] |
|
6 |
RARRES3 |
Retinoic acid receptor responder (tazarotene induced) 3 |
[GenBank:NM_004585.3] |
|
7 |
HLA-DMB |
Major histocompatibility complex, class II, DM beta |
[GenBank:NM_002118.3] |
|
8 |
PSME2 |
Proteasome (prosome, macropain) activator subunit 2 (PA28 beta) |
[GenBank:NM_002818.2] |
|
9 |
C19orf12 |
Chromosome 19 open reading frame 12, transcript variant 2 |
[GenBank:NM_031448.3] |
|
10 |
HLA-DRA |
Major histocompatibility complex, class II, DR alpha |
[GenBank:NM_019111.3] |
|
11 |
CD74 |
CD74 molecule, major histocompatibility complex, class II invariant chain transcript variant 2 |
[GenBank:NM_004355.2] |
|
12 |
IQWD1* |
IQ motif and WD repeats 1 |
[GenBank:BC025262.1] |
|
13 |
APOL3 |
Apolipoprotein L3 |
[GenBank:AF305227.1] |
|
14 |
DUSP3 |
Dual specificity phosphatase 3 |
[GenBank:BC035701.1] |
|
15 |
SEPT4 |
Septin 4, transcript variant 1 |
[GenBank:NM_004574.2] |
|
16 |
CFH |
Complement factor H, transcript variant 1 |
[GenBank:NM_000186.3] |
|
17 |
HLA-DPA1 |
Major histocompatibility complex, class II, DP alpha 1 |
[GenBank:NM_033554.2] |
|
18 |
AIF1 |
Allograft inflammatory factor 1 |
[GenBank:U19713.1] |
|
19 |
OLR1* |
Oxidized low density lipoprotein (lectin-like) receptor 1 |
[GenBank:NM_002543.3] |
|
20 |
ASPHD2 |
Aspartate beta-hydroxylase domain containing 2 |
[GenBank:NM_020437.4] |
|
21 |
LGALS3BP |
Lectin, galactoside-binding, soluble, 3 binding protein |
[GenBank:NM_005567.3] |
|
22 |
PSMB2 |
Proteasome (prosome, macropain) subunit, beta type, 2 |
[GenBank:NM_002794.3] |
|
23 |
TMSB10 |
Thymosin beta 10 |
[GenBank:NM_021103.3] |
|
24 |
STX11 |
Syntaxin 11 |
[GenBank:AF044309.1] |
|
25 |
ZAK |
Sterile alpha motif and leucine zipper containing kinase AZK, transcript variant 1 |
[GenBank:NM_016653.2] |
|
26 |
PSMB8 |
Proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7), transcript variant 2 |
[GenBank:NM_148919.3] |
|
27 |
MSRB2 |
Methionine sulfoxide reductase B2 |
[GenBank:NM_012228.3] |
|
28 |
HLA-DRB3 |
Major histocompatibility complex, class II, DR beta 3 |
[GenBank:BC008987.1] |
|
29 |
ELMO2 |
Engulfment and cell motility 2, transcript variant 1 |
[GenBank:NM_133171.3] |
|
30 |
SSB |
Sjogren syndrome antigen B (autoantigen La) |
[GenBank:NM_003142.3] |
|
31 |
UBE2L3 |
Ubiquitin-conjugating enzyme UbcH7 |
[GenBank:AJ000519.1] |
|
32 |
C16orf75 (MGC24665) |
Chromosome 16 open reading frame 75 |
[GenBank:BC022427.1] |
|
33 |
AGPAT9 (HMFN0839)* |
1-Acylglycerol-3-phosphate O-acyltransferase 9 |
[GenBank:NM_032717.3] |
|
34 |
MTHFD2 |
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
[GenBank:NM_006636.3] |
|
35 |
PSMA5 |
Proteasome (prosome, macropain) subunit, alpha type, 5 |
[GenBank:NM_002790.2] |
|
36 |
ZNF281* |
Zinc finger DNA binding protein 99 (281) |
[GenBank:AF125158.1] |
|
37 |
ROBLD3 (MAPBPIP) |
Roadblock domain containing 3 |
[GenBank:BC024190.2] |
|
|
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*Transcripts underexpressed in patients with septicemic melioidosis when compared to sepsis due to other organisms |
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Pankla et al. Genome Biology 2009 10:R127 doi:10.1186/gb-2009-10-11-r127 |
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