Table 5

The 37 classifiers discriminated sepsis caused by B. pseudomallei from those by other organisms

Rank

Abbreviation

Gene name

Gene accession


1

FAM26F

Homo sapiens family with sequence similarity 26, member F

[GenBank:NM_001010919.1]

2

MYOF

Myoferlin, transcript variant 2

[GenBank:NM_133337.2]

3

LAP3

Leucine aminopeptidase 3

[GenBank:NM_015907.2]

4

HLA-DMA

Major histocompatibility complex, class II, DM alpha

[GenBank:NM_006120.3]

5

WARS

Tryptophanyl-tRNAsynthetase (WRS)

[GenBank:M61715.1]

6

RARRES3

Retinoic acid receptor responder (tazarotene induced) 3

[GenBank:NM_004585.3]

7

HLA-DMB

Major histocompatibility complex, class II, DM beta

[GenBank:NM_002118.3]

8

PSME2

Proteasome (prosome, macropain) activator subunit 2 (PA28 beta)

[GenBank:NM_002818.2]

9

C19orf12

Chromosome 19 open reading frame 12, transcript variant 2

[GenBank:NM_031448.3]

10

HLA-DRA

Major histocompatibility complex, class II, DR alpha

[GenBank:NM_019111.3]

11

CD74

CD74 molecule, major histocompatibility complex, class II invariant chain transcript variant 2

[GenBank:NM_004355.2]

12

IQWD1*

IQ motif and WD repeats 1

[GenBank:BC025262.1]

13

APOL3

Apolipoprotein L3

[GenBank:AF305227.1]

14

DUSP3

Dual specificity phosphatase 3

[GenBank:BC035701.1]

15

SEPT4

Septin 4, transcript variant 1

[GenBank:NM_004574.2]

16

CFH

Complement factor H, transcript variant 1

[GenBank:NM_000186.3]

17

HLA-DPA1

Major histocompatibility complex, class II, DP alpha 1

[GenBank:NM_033554.2]

18

AIF1

Allograft inflammatory factor 1

[GenBank:U19713.1]

19

OLR1*

Oxidized low density lipoprotein (lectin-like) receptor 1

[GenBank:NM_002543.3]

20

ASPHD2

Aspartate beta-hydroxylase domain containing 2

[GenBank:NM_020437.4]

21

LGALS3BP

Lectin, galactoside-binding, soluble, 3 binding protein

[GenBank:NM_005567.3]

22

PSMB2

Proteasome (prosome, macropain) subunit, beta type, 2

[GenBank:NM_002794.3]

23

TMSB10

Thymosin beta 10

[GenBank:NM_021103.3]

24

STX11

Syntaxin 11

[GenBank:AF044309.1]

25

ZAK

Sterile alpha motif and leucine zipper containing kinase AZK, transcript variant 1

[GenBank:NM_016653.2]

26

PSMB8

Proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7), transcript variant 2

[GenBank:NM_148919.3]

27

MSRB2

Methionine sulfoxide reductase B2

[GenBank:NM_012228.3]

28

HLA-DRB3

Major histocompatibility complex, class II, DR beta 3

[GenBank:BC008987.1]

29

ELMO2

Engulfment and cell motility 2, transcript variant 1

[GenBank:NM_133171.3]

30

SSB

Sjogren syndrome antigen B (autoantigen La)

[GenBank:NM_003142.3]

31

UBE2L3

Ubiquitin-conjugating enzyme UbcH7

[GenBank:AJ000519.1]

32

C16orf75 (MGC24665)

Chromosome 16 open reading frame 75

[GenBank:BC022427.1]

33

AGPAT9 (HMFN0839)*

1-Acylglycerol-3-phosphate O-acyltransferase 9

[GenBank:NM_032717.3]

34

MTHFD2

Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

[GenBank:NM_006636.3]

35

PSMA5

Proteasome (prosome, macropain) subunit, alpha type, 5

[GenBank:NM_002790.2]

36

ZNF281*

Zinc finger DNA binding protein 99 (281)

[GenBank:AF125158.1]

37

ROBLD3 (MAPBPIP)

Roadblock domain containing 3

[GenBank:BC024190.2]


*Transcripts underexpressed in patients with septicemic melioidosis when compared to sepsis due to other organisms

Pankla et al. Genome Biology 2009 10:R127   doi:10.1186/gb-2009-10-11-r127

Open Data