Comparison of COMIT z-scores to maximum likelihood Ks scores. There is a clear correlation between mouse-human z-scores and mouse-human Ks based on (a) naïve codon completion or (b) nucleotide-by-nucleotide Ks. These correlations indicate that the qualitative conservation of many motifs is not method-dependent.
Kural et al. Genome Biology 2009 10:R133 doi:10.1186/gb-2009-10-11-r133