Figure 5.

Correlation of DNA methylation with age in amplicon 262. (a) Methylation of amplicon 262 in old and young individuals analyzed without considering genotypes. An age-related highly significant increase in methylation appears to be detected. (b) Distribution of A and G genotypes among old and young individuals in our study. (c) Comparison of DNA methylation in old and young individuals with the same genotypes. This panel shows a re-analysis of the data plotted in (a); error bar represent the standard deviations of the data. This representation of the data clearly indicates that there is no age-related gain of methylation in this amplicon.