Genome Biology

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Correlating measurements across samples improves accuracy of large-scale expression profile experiments

Mariano J Alvarez1, Pavel Sumazin1, Presha Rajbhandari1 and Andrea Califano1,2*

Author Affiliations

1 Joint Centers for Systems Biology, Columbia University, 2960 Broadway, New York, NY 10027-6900, USA

2 Department of Biomedical Informatics and Institute for Cancer Genetics and Herbert Irving Comprehensive Cancer Center, Columbia University, 2960 Broadway, New York, NY 10027-6900, USA

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Genome Biology 2009, 10:R143 doi:10.1186/gb-2009-10-12-r143

Published: 30 December 2009

Additional files

Additional file 1:

Figures S1 to S6.

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Open Data

Additional file 2:

Number of probes, probe clusters, and genes represented on two popular Affymetrix Genechip microarrays after running Cleaner on different expression sets.

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Open Data

Additional file 3:

Probes mapping to FOXM1 and MYB according to Affymetrix and Cleaner annotations.

Format: PDF Size: 86KB Download file

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Open Data