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Custom astrocyte-mediated vasomotor responses to neuronal energy demand
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* Corresponding author: Christopher M Anderson canderson@sbrc.ca
Department of Pharmacology and Therapeutics, University of Manitoba, and Division of Neurodegenerative Disorders, St Boniface Hospital Research Centre, 351 Taché Avenue, Winnipeg, MB R2H 2A6, Canada
Genome Biology 2009, 10:209 doi:10.1186/gb-2009-10-2-209
Published: 16 February 2009Abstract
Astrocytes mediate either constriction or dilation of local brain arterioles in response to synaptic activity. Recent work indicates that the directionality of this response may be dictated by ambient oxygen levels.