EpiGRAPH-generated diagrams highlighting differential histone modification patterns for the promoters of monoallelically versus biallelically expressed genes. This figure displays EpiGRAPH-generated boxplots comparing the promoter regions of genes exhibiting monoallelic (red boxplots) versus biallelic gene expression (yellow boxplots) with respect to their enrichment for two histone modifications, (a) H3 lysine 4 trimethylation and (b) H3 lysine 27 trimethylation. The y-axis plots the frequency of overlap with ChIP-seq tags , which is indicative of the strength of enrichment of the corresponding histone modification. Boxplots are in standard format (boxes show center quartiles, whiskers extend to the most extreme data point, which is no more than 1.5 times the interquartile range from the box) and outliers are shown as crosses.
Bock et al. Genome Biology 2009 10:R14 doi:10.1186/gb-2009-10-2-r14