Research
High tandem repeat content in the genome of the short-lived annual fish Nothobranchius furzeri: a new vertebrate model for aging research
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* Corresponding author: Kathrin Reichwald kathrinr@fli-leibniz.de
1 Leibniz Institute for Age Research - Fritz Lipmann Institute, Beutenbergstr., 07745 Jena, Germany
2 Department of Physiological Chemistry I, University of Würzburg, Biozentrum, Am Hubland, 97074 Würzburg, Germany
3 Department of Human Genetics, University of Würzburg, Biozentrum, Am Hubland, 97074 Würzburg, Germany
4 Current address: Department of Medical Microbiology, Leiden University Medical Centre, 2300 RC Leiden, The Netherlands
5 Current address: Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein, Campus Kiel, Schittenhelmstr., 24105 Kiel, Germany
Genome Biology 2009, 10:R16 doi:10.1186/gb-2009-10-2-r16
Published: 11 February 2009Additional files
Additional data file 1:
Coding sequences identified in random genomic sequence samples of medaka, stickleback, tetraodon and zebrafish, their genome sizes, and inferred N. furzeri genome size are given.
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Additional data file 2:
N. furzeri GRZ gene fragments identified by BLASTX searches in Swiss-Prot/TrEMBL.
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Additional data file 3:
Flow cytometry measurements to estimate the N. furzeri genome size.
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Additional data file 4:
G+C histograms of N. furzeri strain MZM-0403 and the closely related species N. kunthae.
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Additional data file 5:
Microsatellite frequencies of N. furzeri GRZ.
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Additional data file 6:
The subgroup of N. furzeri GRZ gene fragments lacking homologs in medaka, stickleback, tetraodon, and zebrafish.
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Additional data file 7:
Chromosomal locations and accession numbers of sequences used for analyses of aging related genes.
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Additional data file 8:
Conservation of the N. furzeri GRZ major rRNA cluster in tetraodon and human.
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Additional data file 9:
Genotypes of microsatellites analyzed in N. furzeri strains GRZ and MZM-0403 and the closely related species N. kunthae.
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Additional data file 10:
Analysis of 19 gene-associated markers in N. furzeri strains GRZ and MZM-0403 and N. kunthae.
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Additional data file 11:
Primers used to clone and sequence five aging related genes in N. furzeri GRZ.
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Additional data file 12:
Nucleotide and amino acid sequences used for phylogenetic analyses.
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