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The need for speed

Paul Flicek

Author Affiliations

European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK

Genome Biology 2009, 10:212  doi:10.1186/gb-2009-10-3-212

Published: 27 March 2009

Abstract

DNA sequence data are being produced at an ever-increasing rate. The Bowtie sequence-alignment algorithm uses advanced data structures to help data analysis keep pace with data generation.