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Rac and Rho driving tumor invasion: who's at the wheel?
1 Center for Oncology and Cell Biology, The Feinstein Institute for Medical Research at North Shore-LIJ, 350 Community Drive, Manhasset, NY 11030, USA
2 Gruss Lipper Biophotonics Center, Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
Genome Biology 2009, 10:213 doi:10.1186/gb-2009-10-3-213
Published: 6 March 2009Abstract
Genome-wide analysis of regulators of Rho-family small GTPases has identified critical elements that control the morphology and invasive behavior of melanoma cells.
