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Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Ben Langmead*, Cole Trapnell, Mihai Pop and Steven L Salzberg

Author Affiliations

Center for Bioinformatics and Computational Biology, Institute for Advanced Computer Studies, University of Maryland, College Park, MD 20742, USA

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Genome Biology 2009, 10:R25  doi:10.1186/gb-2009-10-3-r25

Published: 4 March 2009

Additional files

Additional data file 1:

Presented are supplementary discussions, tables, and figures pertaining to algorithms for navigating the Burrows-Wheeler transform, the full four-phase version of the alignment algorithm that incorporates the reverse-complement, index construction, and components of the index.

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